propanediol dehydratase การใช้

• This is an example of bioengineering that likewise provides evidence in support of the selfish operon hypothesis . 1, 2-propanediol is dehydrated to propionaldehyde by propanediol dehydratase, which requires vitamin B12 as a cofactor.
• This induction is mediated by the global regulator proteins Crp and ArcA ( sensing cyclic AMP and anaerobic conditions respectively ), and the regulatory protein PocR, which is the transcriptional activator for both the " pdu " and the " cob " loci ( the operon necessary for the synthesis of vitamin B12, a required cofactor for propanediol dehydratase ).